The Risk of In-Hospital Mortality in Elderly Patients with Pancreatic Pseudocyst Admitted Emergently is 4.5 Times Greater than that in Adults
Mackenzie Leonard1 BS, Abbas Smiley2 MD/PhD, Cailan L Feingold1 BS, Rifat Latifi3 MD, FACS, FICS, FKCS
1New York Medical College, School of Medicine, Valhalla NY, US
2School of Medicine, University of Rochester, Rochester, NY.
3Adjunct Professor of Surgery, University of Arizona, Tucson, AZ, US
* Correspondence: [email protected]
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Abstract
Background: Adult and elderly patients admitted emergently with the primary diagnosis of pseudocyst of the pancreas (PCP) have high of morbidity and mortality.
Objective: The aim of our study was to examine the risk factors associated with in-hospital mortality in both adult and elderly patients with PCP admitted emergently.
Design/Methods: Patients with PCP were analyzed using the National Inpatient Sample (NIS) database, 2005-2014. The clinical data, mortality, and demographics were collected and analyzed using stratified analyses and multivariable logistic regression model with backward elimination to find the factors associated with increased mortality.
Results: There were a total of 9,179 patients included in the study of which 6,769 (73.44%) were adults (age <65 years) and 2,410 (26.56%) elderly patients (age 65+ years). The mean (SD) age was 46 (11.4) years in the adult cohort and 74.5 (7.3) years in the elderly. Of the adult patients, 4,077 (60.2%) were male and 2,692 (39.8%) were female. The elderly patient cohort had 1,130 (48.3%) males and 1,208 (51.7%) females. Overall, mortality was 0.6% in adults and 2.7% in the elderly. 47.2% in adults and 41.3% in the elderly underwent surgical intervention. Age, hospital length of stay and comorbidities like respiratory diseases, coagulopathy, cardiac diseases, trauma, burns and poisons, and genitourinary system diseases were all significantly associated with increased odds of mortality.
Conclusions: In conclusion, our study stratified patient characteristics based on gender, mortality, and treatment type. Additionally, we found that age, hospital length of stay and multiple comorbidities are significantly associated with increased odds of mortality in PCP patients.